Monthly Archives: October 2009

Word order and Broca’s region: Evidence for a supra-syntactic perspective

It has often been suggested that the role of Broca’s region in sentence comprehension can be explained with reference to general cognitive mechanisms (e.g. working memory, cognitive control). However, the (language-related) basis for such proposals is often restricted to findings on English. Here, we argue that an extension of the database to other languages can shed new light on the types of mechanisms that an adequate account of Broca’s region should be equipped to deal with. This becomes most readily apparent in the domain of word order variations, which we examined in German verb-final sentences using event-related fMRI. Our results showed that activation in the pars opercularis – a core subregion of Broca’s area – was not only modulated by the relative ordering of subject and object, but also by a further factor known to affect word order in a number of languages, namely referentiality. Notably, the finding provides the first demonstration of a word order-related activation difference within subject-initial sentences in this region. Additional parametric analyses using individual behavioral data as predictors further attest to the independence of the pars opercularis activation from: (a) sentence acceptability, and (b) difficulty in performing the experimental (judgment) task. We argue that these and related findings attest to the need for a processing mechanism that can manipulate predicate-independent, interacting and hierarchically structured relational representations during real time comprehension. These properties pose a challenge to existing accounts of pars opercularis function.

from Brain and Language

Burow’s solution-induced acute sensorineural hearing loss: Report of two cases

This is the report of rare cases to show the potential ototoxicity of Burow’s solution in clinical use. We encountered two cases of acute sensorineural hearing loss occurring after the administration of 8% Burow’s solution (pH 2.93) into the tympanic cavities. Prior to treatment, both cases presented with tympanic membrane perforations in the posterior and inferior portions and a small amount of serous discharge. Fortunately, hearing loss recovered almost completely except for high tones within a few weeks. These two case reports demonstrate that the ototoxicity of Burow’s solution should be considered when it is used to treat otitis media accompanied by tympanic membrane perforation.

from Auris Nasus Larynx

Education, Occupation, Noise Exposure History and the 10-yr Cumulative Incidence of Hearing Impairment in Older Adults

The purpose of this study was to determine the 10-yr cumulative incidence of hearing impairment and associations of education, occupation and noise exposure history with the incidence of hearing impairment in a population-based cohort study of 3753 adults ages 48-92 years at the baseline examinations during 1993-1995 in Beaver Dam, WI. Hearing thresholds were measured at baseline, 2.5 yr, 5 yr, and 10-yr follow-up examinations. Hearing impairment was defined as a pure-tone average (PTA) > 25 dB HL at 500, 1000, 2000, and 4000 Hz. Demographic characteristics and occupational histories were obtained by questionnaire. The 10-yr cumulative incidence of hearing impairment was 37.2%. Age (5 yr; Hazard Ratio (HR)=1.81), sex (M v W; HR=2.29), occupation based on longest held job (Production/Operations/Farming vs others; HR=1.34), marital status (unmarried vs married; HR=1.29) and education (<16 vs 16+ yrs; HR=1.40) were associated with the 10 yr incidence. History of noisy jobs was not associated with the 10-yr incidence of hearing impairment. The risk of hearing impairment was high, with women experiencing a slightly later onset. Markers of socioeconomic status were associated with hearing impairment, suggesting that hearing impairment in older adults may be associated with modifiable lifestyle and environmental factors, and therefore, at least partially preventable.

from Hearing Research

Electrophysiological attention effects in a virtual cocktail-party setting

The selection of one of two concurrent speech messages for comprehension was investigated in healthy young adults in two event-related potential experiments. The stories were presented from virtual locations located 30 degrees to the left and right azimuth by convolving the speech message by the appropriate head-related transfer function determined for each individual participant. In addition, task irrelevant probe stimuli were presented in rapid sequence from the same virtual locations. In experiment 1, phoneme probes (/da/ voiced by the same talkers as attended and unattended messages) and band-pass filtered noise probes were presented. Phoneme probes coinciding with the attended message gave rise to a fronto-central negativity similar to the Nd-attention effect relative to the phoneme probes coinciding with the unattended speech message, whereas noise probes from the attended message’s location showed a more positive frontal ERP response compared to probes from the unattended location resembling the so-called rejection positivity. In experiment 2, phoneme probes (as in exp. 1) and frequency-shifted (+400 Hz) were compared. The latter were characterized by a succession of negative and positive components that were modulated by location. The results suggest that at least two different neural mechanisms contribute to stream segregation in a cocktail-party setting: enhanced neural processing of stimuli matching the attended message closely (indexed by the Nd-effect) and rejection of stimuli that do not match the attended message at the attended location only (indexed by the rejection positivity).

from Brain Research

Implantation of Esterified Hyaluronic Acid in Microdissected Reinke’s Space After Vocal Fold Microsurgery: Short- and Long-Term Results

In this study are reported the laryngeal and vocal results obtained after a microflap excision of benign vocal fold (VF) lesions and immediate implantation of esterified hyaluronic acid (EHA) in the surgical wound. In a previous pilot study on 11 cases, we have shown an excellent tolerance of this bioimplant. The objectives are to confirm the innocuity of the technique, to demonstrate the laryngeal and vocal evolution at short and long term, and to evaluate the eventual positive impact of EHA implantation on the pliability of the superficial layer of the lamina propria (SLLP) and on voice. This is a prospective and comparative study on 83 patients suffering from various benign VF lesions. Thirty-three patients were implanted with EHA, whereas 50 patients did not undergo implantation at the end of the microsurgical procedure.All patients undergo rigid laryngoscopy and microflap excision procedure under general anesthesia. After freeing up of the Reinke’s space and creation of a mucosal microflap, a few fibers of EHA are inserted in the surgical wound, before closure of the incision with fibrin glue. Serial laryngeal and vocal assessments are performed in all patients using videostroboscopy (Wolff and Xion), perceptual and objective voice evaluation (MDVP software, Kay Elemetrics), and phonatory function measurements (Aerophone II). Pre- and early postoperative means are compared by analysis of variance. Delayed and long-term evolution of laryngeal and vocal data are compared by means of nonparametric statistical methods. The longest follow-up in the implanted group is 4 years. Early postoperative results are similar in both groups: a significant improvement of a majority of laryngeal and vocal data is observed after microsurgery. In the long term, the two groups exhibit a different behavior: further improvement of voice, as an ongoing process, is only observed in the EHA implanted group, together with improvement of some videostroboscopic characteristics. The nonimplanted group remains stable, with no further improvement of the voice quality obtained after microsurgery. Excellent short- and long-term tolerance of EHA implantation is confirmed by this larger series. The use of EHA implant in microdissected SLLP is safe and leads to good laryngeal and vocal outcomes in the treated patients. More interestingly, treated cases exhibit a continuous improvement over a long period of time.

from the Journal of Voice

Vocal Fold Nodules: Morphological and Immunohistochemical Investigations

The objective of this study was to investigate the morphological and immunohistochemical characteristics of vocal fold nodules. The study design was prospective and retrospective. For the histological study, we reviewed 15 slides from the surgical cases of vocal fold nodules, in which we analyzed epithelium, basal membrane (bm), and lamina propria. For the transmission and scanning electron microscopy (TEM, SEM) studies, five new cases on vocal fold nodules were included. Immunohistochemistry study was carried out in the 15 specimens, using antifibronectin, antilaminin, and anticollagen IV antibodies. The main histological alterations were epithelial hyperplasia (73.33%), basement membrane thickening (86.66%), edema, and fibrosis (93.33%). SEM—reduction in mucous lacing and increase in the desquamating cells, without epithelial erosion. TEM—hyperplasia of the epithelium, enlargement of the intercellular junctions, which was filled by fluid, subepithelial thickening of the lamina reticularis, and break points in the basal membrane. Immunohistochemistry—we identified greater immunoexpression of fibronectin on the basal membrane, on the lamina propria, and around the vessels. Antilaminin and anticollagen IV antibodies showed higher pigmentation on the endothelium of the vessels than that on the basal membrane. In vocal fold nodules, combined assessment using light microscopy, electron microscopy, and immunohistochemistry can reveal important morphological details useful in characterizing these lesions.

from the Journal of Voice

Evaluation for language and speech development in Kabuki make-up syndrome: A case report

Kabuki make-up syndrome (KMS) is defined as a rare syndrome with mental retardation, growth deficiency and multiple anomalies of unknown cause. Cases have a characteristic facial appearance of broad and low auricles, wide forehead, broad and flattened nose root. In this article, 4-year, 10-month-old boy with speech delay reported due to characteristics of the facial appearance is considered as KMS, a rare syndrome. Otological, audiological and developmental evaluation of the patient consisted of six parameters. (1) ENT examination: normal. (2) Audiological findings were at normal hearing levels. (3) General development (according to the Denver II test), was normal. (4) Language and speech development: receptive language development was 2 years more than the chronological age. However in expressive language development, there was 5-month delay which was likely to complete by training in a short time. (5) The development of speech sounds and articulation: the delay is observed in CVC words. Speech sounds of /l/, /t/, /r/ and /g/ were evaluated as “distorted expression”. He used /v/ instead of /l/; /y/ instead of /r/; /d/ instead of /g/. (6) Observations: diffident, deficit in self-confidence, and difficulty in communicating have been observed.Unlike the cases in literature, mental retardation, growth deficiency and learning difficulties were not found in our case with KMS. Normal findings were obtained in five parameters. Only the /l/, /r/ and /g/ speech sounds were expressed as distorted. For our case, we planned to follow him in the future to see whether developmental and central auditory processing disorders will occur or not.

from the International Journal of Pediatric Otorhinolaryngology

Can input explain children’s me-for-I errors?

English-speaking children make pronoun case errors producing utterances where accusative pronouns are used in nominative contexts (me do it). We investigate whether complex utterances in the input (Let me do it) might explain the origin of these errors. Longitudinal naturalistic data from seventeen English-speaking two- to four-year-olds was searched for 1psg accusative-for-nominative case errors and for all 1psg preverbal pronominal contexts. Their caregivers’ data was also searched for 1psg preverbal pronominal contexts. The data show that the children’s proportional use of me-for-I errors correlated with their caregivers’ proportional use of me in 1psg preverbal contexts. Furthermore, the verbs that children produced in me-error utterances appeared in complex sentences containing me in the input more often than verbs that did not appear in me-for-I errors in the children’s speech. These findings are discussed in the context of current explanations for children’s case marking errors.

from the Journal of Child Language

Early vocabulary development in Mandarin (Putonghua) and Cantonese

Parent report instruments adapted from the MacArthur-Bates Communicative Development Inventories (CDI) examined vocabulary development in children aged 0 ; 8 to 2 ; 6 for two Chinese languages, Mandarin (n=1694) and Cantonese (n=1625). Parental reports suggested higher overall scores for Mandarin- than for Cantonese-speaking children from approximately 1 ; 4 onward. Factors relevant to the difference were only-child status, monolingual households and caregiver education. In addition to the comparison of vocabulary scores overall, the development of noun classifiers, grammatical function words common to the two languages, was assessed both in terms of the age and the vocabulary size at which these terms are acquired. Whereas age-based developmental trajectories again showed an advantage for Beijing children, Hong Kong children used classifiers when they had smaller vocabularies, reflecting the higher frequencies and greater precision of classifier use in adult Cantonese. The data speak to the importance of using not just age, but also vocabulary size, as a metric by which the acquisition of particular linguistic elements can be examined across languages.

from the Journal of Child Language

Emerging temporality: past tense and temporal/aspectual markers in Spanish-speaking children’s intra-conversational narratives

This study describes how young Spanish-speaking children become gradually more adept at encoding temporality using grammar and discourse skills in intra-conversational narratives. The research involved parallel case studies of two Spanish-speaking children followed longitudinally from ages two to three. Type/token frequencies of verb tense, temporal/aspectual markers and narrative components were analyzed to explore interrelationships among grammatical and discourse skills. Children progressed from scattered unsystematic means of encoding temporality to mastering a basic linguistic system that included devices to mark location of events, temporal relations and aspectual meanings. The consolidation of perfective past tense to express narrative events marked a crucial developmental point which preceded an explosion of additional verb tenses and temporal markers. The value of spontaneous language data, and the need to study grammar and discourse simultaneously to construct a comprehensive developmental picture are highlighted. Results are discussed in relation to theoretical proposals on the development of temporality.

from the Journal of Child Language

From sound to syntax: phonological constraints on children’s lexical categorization of new words

Two studies examined the role of phonological cues in the lexical categorization of new words when children could also rely on learning by exclusion and whether the role of phonology depends on extensive experience with a language. Phonological cues were assessed via phonological typicality – an aggregate measure of the relationship between the phonology of a word and the phonology of words in the same lexical class. Experiment 1 showed that when monolingual English-speaking seven-year-olds could rely on learning by exclusion, phonological typicality only affected their initial inferences about the words. Consistent with recent computational analyses, phonological cues had stronger impact on the processing of verb-like than noun-like items. Experiment 2 revealed an impact of French on the performance of seven-year-olds in French immersion when tested in a French language environment. Thus, phonological knowledge may affect lexical categorization even in the absence of extensive experience.

from the Journal of Child Language

How and when auditory action effects impair motor performance

Abstract Music performance is characterized by complex cross-modal interactions, offering a remarkable window into training-induced long-term plasticity and multimodal integration processes. Previous research with pianists has shown that playing a musical score is affected by the concurrent presentation of musical tones. We investigated the nature of this audio-motor coupling by evaluating how congruent and incongruent cross-modal auditory cues affect motor performance at different time intervals. We found facilitation if a congruent sound preceded motor planning with a large Stimulus Onset Asynchrony (SOA −300 and −200 ms), whereas we observed interference when an incongruent sound was presented with shorter SOAs (−200, −100 and 0 ms). Interference and facilitation, instead of developing through time as opposite effects of the same mechanism, showed dissociable time-courses suggesting their derivation from distinct processes. It seems that the motor preparation induced by the auditory cue has different consequences on motor performance according to the congruency with the future motor state the system is planning and the degree of asynchrony between the motor act and the sound presentation. The temporal dissociation we found contributes to the understanding of how perception meets action in the context of audio-motor integration.

from Experimental Brain Research

HearingPlanet’s New Blog Keeps Readers Up-to-Date

HearingPlanet, the leading internet resource for buying hearing aids, has developed and released a new on-site blog that presents top stories related to a wide variety of hearing aid and digital hearing aid topics.

from PRWeb.com

Important Facts on Children and Speech or Language Impairments

If you’re looking for some basic information on adolescent speech or language impairment then check out this informative article at Disabled World. The article outlines the definition of a speech or language impairment, the difference between speech and language, the education of speech-language pathologists and a few basic facts on speech/language impairments.

from Presence TeleCare

Newborn hearing screening: An outpatient model

Objective
The purpose of this study was to assess the feasibility of implementing an outpatient model of a newborn hearing screening program with a particular focus on determining how compliance with the follow-up appointment related to specific socio-economic and demographic factors associated with the mother.

Method
Mothers who delivered their babies in public hospitals in Recife, northeast Brazil, were invited to participate in a two-step program. In Step 1 they were interviewed with regard to specific socio-economic and demographic factors, and then scheduled for a hearing screening test for their baby 1 month after discharge. In Step 2, the baby’s hearing was screened using transient otoacoustic emissions.

Results
A total of 1035 mothers consented to participate in Step 1, but only 149 returned to participate in Step 2 (14.3%). Analysis of the socio-economic and demographic factors indicated that mothers who did not comply with the scheduled newborn hearing screening (NHS) test generally had less than a high school education and came from primarily lower income families who lived in rural areas outside of Recife.

Conclusion
The results of this study highlight some socio-economic and demographic factors of the population of northeast Brazil that contribute to a low compliance rate for an outpatient model of a newborn hearing screening program. Possible solutions to the low compliance rate are considered.

from the International Journal of Pediatric Otorhinolaryngology

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