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Auditory N1 as a change-related automatic response

These results support the idea that On-N1 is a change-related component elicited by a sound pressure change.

from Neuroscience Research

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A postsleep decline in auditory evoked potential amplitude reflects sleep homeostasis

Conclusions
The decline in AEP amplitude after a night of sleep may reflect a homeostatic reduction in synaptic strength.

from Clinical Neurophysiology

A postsleep decline in auditory evoked potential amplitude reflects sleep homeostasis

Conclusions
The decline in AEP amplitude after a night of sleep may reflect a homeostatic reduction in synaptic strength.

from Clinical Neurophysiology

Does Audiovisual Speech Offer a Fountain of Youth for Old Ears? An Event-Related Brain Potential Study of Age Differences in Audiovisual Speech Perception

The current study addressed the question whether audiovisual (AV) speech can improve speech perception in older and younger adults in a noisy environment. Event-related potentials (ERPs) were recorded to investigate age-related differences in the processes underlying AV speech perception. Participants performed an object categorization task in three conditions, namely auditory-only (A), visual-only (V), and AVspeech. Both age groups revealed an equivalent behavioral AVspeech benefit over unisensory trials. ERP analyses revealed an amplitude reduction of the auditory P1 and N1 on AVspeech trials relative to the summed unisensory (A + V) response in both age groups. These amplitude reductions are interpreted as an indication of multisensory efficiency as fewer neural resources were recruited to achieve better performance. Of interest, the observed P1 amplitude reduction was larger in older adults. Younger and older adults also showed an earlier auditory N1 in AVspeech relative to A and A + V trials, an effect that was again greater in the older adults. The degree of multisensory latency shift was predicted by basic auditory functioning (i.e., higher hearing thresholds were associated with larger latency shifts) in both age groups. Together, the results show that AV speech processing is not only intact in older adults, but that the facilitation of neural responses occurs earlier in and to a greater extent than in younger adults. Thus, older adults appear to benefit more from additional visual speech cues than younger adults, possibly to compensate for more impoverished unisensory inputs because of sensory aging.

from Psychology and Aging

Late auditory evoked potentials in elderly long-term hearing-aid users with unilateral or bilateral fittings

This study investigated the effects of long-term unilateral and bilateral amplification on central auditory processing in elderly people with symmetrical hearing loss using late auditory evoked potentials. It was hypothesized that in the unilateral setting stimulation of the aided ear would yield an acclimatization effect with larger amplitudes and shorter latencies of the components P1, N1 and P2 compared to those of the unaided ear. Auditory evoked potentials were elicited by 500, 1000 and 2000 Hz pure tones at 55, 70 and 85 dB SPL presentation level delivered either to the left or right ear. Unilaterally and bilaterally fitted experienced hearing-aid users and a control group of normally hearing adults, all aged at least 60 years, participated. The responses of the unilateral hearing-aid users did not differ significantly for any of the components P1, N1 or P2 between the aided and unaided ears, but a significant interaction between ear and frequency was present for P2 amplitudes. P2 amplitudes were significantly smaller for the 0.5- and 1-kHz stimuli and tended to be larger for the 2-kHz stimulus in the aided ear suggesting an acclimatization effect. Larger P2 amplitudes were observed in the unilaterally fitted group, which was interpreted as a correlate of more effortful auditory processing in unilaterally fitted people.

from Hearing Research

Behavioral and Electrophysiologic Binaural Processing in Persons with Symmetric Hearing Loss

Conclusions:

The behavioral and electrophysiological measures used in the present study clearly showed evidence of reduced binaural processing in ∼10 of the subjects in the present study who had symmetrical pure-tone sensitivity. These results underscore the importance of understanding binaural auditory processing and how these measures may or may not identify functional auditory problems.

from the Journal of the American Academy of Audiology

Stuttering Treatment Control Using P300 Event-Related Potentials

Positron Emission Tomography studies during speech have indicated a failure to show the normal activation of auditory cortical areas in stuttering individuals. In the present study, P300 event-related potentials were used to investigate possible effects of behavioral treatment on the pattern of signal amplitude and latency between waves. In order to compare variations in P300 measurements, a control group paired by age and gender to the group of stutterers, was included in the study. Findings suggest that the group of stutterers presented a significant decrease in stuttering severity after the fluency treatment program. Regarding P300 measurements, stutterers and their controls presented results within normal limits in all testing situations and no significant statistical variations between pre and post treatment testing. When comparing individual results between the testing situations, stutterers presented a higher average decrease in wave latency for the right ear following treatment. The results are discussed in light of previous P300 event-related potentials and functional imaging studies with stuttering adults

from Journal of Fluency Disorders

Steady-state analysis of auditory evoked potentials over a wide range of stimulus repetition rates: Profile in adults

Objective: Quasi-steady-state responses were assessed over a wide range of stimulus repetition rates embracing well the traditionally measured transient AEPs (obligatory auditory evoked potentials of all latencies). Repetition rates of ≤10 Hz have received little attention in the context of the ASSR stimulus-response analysis approach which is speculated to provide technical advantages, if not additional information, over more traditional transient stimulus-response paradigms. Design: A measure introduced and defined as the sum of the response at the stimulus frequency and its harmonics. The magnitude of steady-state responses were measured at repetition rates from 0.75 to 80 Hz, using trains of repeated tone-burst stimuli. Study sample: Twenty-five normal-hearing adults. Results: Results show that the magnitudes of the response across repetition rates are largest at the two lowest rates, following trends expected from the transient AEP literature. Good reliability overall was observed for the harmonic sum. Conclusions: The analysis methods used in this paper may give information that will have application for clinical testing. Of pragmatic importance is that the rate profile could be determined without subjective wave identification and/or interpretation, and thus by a method that is inherently more objective than conventional AEP tests.

from the International Journal of Audiology

Cochlear Implantation in Brown–Vialetto–Van-Laere syndrome

These poor clinical outcomes appear to be related to retrocochlear and probable central auditory pathway degeneration.

from the Journal of Laryngology and Otology

Long latency auditory evoked potentials in children with phonological disorder*

children with phonological disorder present altered P300 suggesting involvement of the central auditory pathway, probably due to alterations in the auditory processing, presenting improvement in all components of LLAEP results after speech therapy.

from Pró-Fono Revista de Atualização Científica

Study of suppression effect in the brainstem auditory evoked potential*

the present study indicated increased latencies and reduced amplitudes of waves I, III and V with contralateral noise, when comparing the situations with and without noise. These results suggest a possible influence of the efferent auditory system on the response modulation of Brainstem auditory evoked potential when contralateral white noise is used.

from Pró-Fono

Study of auditory evoked potentials in autism

CONCLUSION: autistic individuals present altered BAEP and P300, suggesting impairment in the brainstem auditory pathway and corticals / subcorticals areas.

from Pró-Fono Revista de Atualização Científica

Aging alters the perception and physiological representation of frequency: Evidence from human FFR recordings.

Older adults, even with clinically normal hearing sensitivity, have auditory perceptual deficits relative to their younger counterparts. This difficulty may in part, be related to a decline in the neural representation of frequency. The purpose of this study was to examine the effect of age on behavioral and physiological measures of frequency representation. Thirty two adults (ages 22 – 77), with hearing thresholds < 25 dB HL at octave frequencies 0.25 – 8.0 kHz, participated in this experiment. Frequency discrimination difference limens (FDLs) were obtained at 500 and 1000 Hz using a two-interval, two-alternative forced choice procedure. Linear regression analyses showed significant declines in FDLs at both frequencies as age increased. Frequency-following responses (FFRs) were elicited by 500 and 1000 Hz tonebursts, as well as at frequencies within and outside those FDLs. Linear regression of FFR phase coherence and FFR amplitude at frequencies at and slightly below 1000 Hz showed significant decreases as age increased. Therefore, pitch discrimination, as measured by FDLs, and neural representation of frequency, as reflected by FFR, declined as age increased. Although perception and neural representation concurrently declined, one was not predictive of the other.

from Hearing Research

Auditory Steady-State Evoked Responses for Preterm and Term Neonates

Hearing thresholds were estimated in normal-hearing term and preterm neonates of <35 weeks of age using multiple-stimulus auditory steady-state responses (ASSRs). The tresholds, expressed in decibel sound pressure level, at signal frequencies of 500, 1000, 2000 and 4000 Hz were 44.30 ± 9.88, 27.80 ± 6.79, 26.77 ± 6.09 and 32.87 ± 6.12 for the term group and 49.11 ± 9.44, 26.38 ± 6.59, 26.74 ± 7.57 and 35.90 ± 8.23 for the preterm group. Significant threshold differences were measured between the groups at 500 and 4000 Hz, while the thresholds at 1000 and 2000 Hz were similar. The signal and noise levels as well as signal-to-noise ratio of responses were also measured and found to be similar. These results indicate that ASSRs can be effectively measured with a similar signal-to-noise ratio in both groups, but that there is a significant maturational effect occurring during gestation at the level of structures which participate in the formation of the ASSR at 500 and 4000 Hz.

from Audiology & Neuro-Otology

Auditory Steady-State Evoked Responses for Preterm and Term Neonates

Hearing thresholds were estimated in normal-hearing term and preterm neonates of <35 weeks of age using multiple-stimulus auditory steady-state responses (ASSRs). The tresholds, expressed in decibel sound pressure level, at signal frequencies of 500, 1000, 2000 and 4000 Hz were 44.30 ± 9.88, 27.80 ± 6.79, 26.77 ± 6.09 and 32.87 ± 6.12 for the term group and 49.11 ± 9.44, 26.38 ± 6.59, 26.74 ± 7.57 and 35.90 ± 8.23 for the preterm group. Significant threshold differences were measured between the groups at 500 and 4000 Hz, while the thresholds at 1000 and 2000 Hz were similar. The signal and noise levels as well as signal-to-noise ratio of responses were also measured and found to be similar. These results indicate that ASSRs can be effectively measured with a similar signal-to-noise ratio in both groups, but that there is a significant maturational effect occurring during gestation at the level of structures which participate in the formation of the ASSR at 500 and 4000 Hz.

from Audiology & Neuro-Otology