Blog Archives

Early subclinical cochlear dysfunction in myotonic dystrophy type 1

Conclusions:  Our study indicates that cochlear impairment in DM1 is present, even in patients without evidence of hearing loss at a standard audiometric analysis. Hence, in the current clinical practice, an assessment of cochlear function by TEOAE recording may be useful in DM1 patients to identify precocious signs of cochlear dysfunction.

from the European Journal of Neurology

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Relationships among Standard and Wideband Measures of Middle Ear Function and Distortion Product Otoacoustic Emissions

Conclusions:

The implications are as follows: (1) WATFs, which can be obtained with the same probe microphone system as DPOAEs, could be used as a supplement to tympanometry in a diagnostic test battery, and the relationship between Ya measured on the two systems could be used for verification, and (2) Ya and ER measures from WATFs at both DPOAE stimulus frequencies account for some of the variability observed in DPOAE levels at f2 = 4000 Hz in normal ears.

from the Journal of the American Academy of Audiology

The use of transient evoked otoacoustic emissions as a hearing screen following grommet insertion

Conclusion: Transient evoked otoacoustic emission testing offers a sensitive means of detecting hearing loss of ≥30 dB following grommet insertion in children. However, the use of such testing as a screening tool may miss some cases of mild hearing loss.

from the Journal of Laryngology and Otology

Cochlear function in 1-year-old term infants born with hypoxia-ischaemia or low Apgar scores

Conclusions: DPOAE pass rates, mainly at 1 and 2 kHz, were decreased at 1 year in infants born with perinatal HI and low Apgar scores, suggesting a relative poor cochlear function. Further studies are needed to ascertain the hearing acuity.

from the Journal of Paediatrics and Child Health

Effect of chronic exposure to cellular telephone electromagnetic fields on hearing in rats

Exposure to the electromagnetic field emitted by cellular telephones, for 6 hours a day for 30 consecutive days, had no effect on the hearing of newborn or adult rats, at the outer ear, middle ear or cochlear level.

from the Journal of Laryngology and Otology

Unstable distortion-product otoacoustic emission phase in Menière’s disease

The presence of endolymphatic hydrops as a marker of Menière’s disease (MD) suggests abnormal pressure in the intralabyrinthine compartments of patients and excessive stiffness of sound-sensitive structures. Otoacoustic emissions (OAEs) have been reported to respond to changes in the ear’s stiffness, including those produced by intracranial pressure steps, by a characteristic phase shift around 1 kHz, thereby suggesting a noninvasive means of monitoring MD. Here, body tilt was used for modulating intracranial pressure in forty-one patients with definite MD who were tentatively measured at two stages, with and without active symptoms. Their distortion-product OAEs (DPOAEs) were dynamically monitored around 1 kHz every few seconds in response to body tilt. In a control sample of thirty normal ears, the maximum phase rotation of DPOAEs produced by body tilt was between –18° and +37°. In MD ears with the complete set of symptoms, the posture-induced phase shifts in 32 out of 35 tests fell outside the normative interval, and in 10 tests, although DPOAEs were well above noise floor, their phase was always so abnormally erratic that body tilt produced hardly any additional effect. When MD ears were asymptomatic, nine out of 32 posture tests were abnormal. The excessive DPOAE phase shift is consistent with either a too stiff cochlear partition or a displacement of the operating point of outer hair cells by endolymphatic hydrops.

from Hearing Research

Associations between Diet and Both High and Low Pure Tone Averages and Transient Evoked Otoacoustic Emissions in an Older Adult Population-Based Study

Conclusions:

These data suggest that nutrients with known roles in redox homeostasis and vascular health are associated with auditory function measures in a human population. Further investigation is warranted to determine direct and indirect influences of dietary intake on measures of auditory function and to explore which nutrients/nutrient combinations are predictive of SNHL.

from the Journal of the American Academy of Audiology

Impaired Cochlear Function Correlates with the Presence of Tinnitus and Its Estimated Spectral Profile

from Hearing Research

A comparison of audiometric and objective methods in hearing screening of school children. A preliminary study

Conclusions
Screening of school children is feasible with a combination of automated audiometry and tympanometry with time requirements equal to 3 min per subject.

from the International Journal of Pediatric Otorhinolaryngology

Otoacoustic emissions growth rate threshold – distortion product in neonates*

the procedure was feasible for the neonatal population revealing mean thresholds of up to 60dB for both frequencies. Even though participants presented elevated thresholds, robust amplitude responses were observed.

from Pró-Fono Revista de Atualização Científica

Cochlear active mechanisms in young normal-hearing subjects affected by willams syndrome: Time-frequencyanalysis of otoacoustic emissions

The aim of this study was to investigate the functionality of cochlear active mechanisms in normal hearing subjects affected by Williams syndrome (WS). Transient evoked otoacoustic emissions (TEOAE) were recorded in a group of young WS subjects and a group of typically developing control subjects, all having normal hearing thresholds and normal middle ear functionality. We also analysed the narrow-band frequency components of TEOAEs, extracted from the broad-band TEOAE recordingsby using a time-frequency analysis algorithm based on the Wavelet transform. We observed that TEOAEs and the frequency components extracted from TEOAEs measured in WS subjects had significantly lower energy compared to the controls. Also, the narrow-band frequency components of TEOAEs measured in WS subjects had slightly increased latency compared to the controls. Overall, results would suggest a subtle (i.e., sub‑clinical) dysfunction of the cochlear active mechanisms in WS subjects with otherwise normal hearing. Also, results point out the relevance of using otoacoustic emissions in the audiological evaluation and monitoring of WS subjects to early identify possible subtle auditory dysfunctions, before the onset of mild or moderate hearing loss that could exacerbate language or cognitive impairments associated with WS.

from Hearing Research

Neonatal hearing screening in Benin City

The screening tests suggest a high crude prevalence (6.5%) of bilateral neonatal hearing impairment in Benin City necessitating confirmation and intervention. The study fortifies the need for hearing screening among all new born in developing countries.

from the International Journal of Pediatric Otorhinolaryngology

Sensory dysmodulation in vestibular migraine

These results provide support for the notion of interictal auditory sensory dysmodulation in an as yet unidentified subset of migraineurs with vestibular migraine. Laryngoscope, 2010

from The Laryngoscope

Quantitative analysis of cochlear active mechanisms in tinnitus subjects with normal hearing sensitivity: Time–frequency analysis of transient evoked otoacoustic emissions and contralateral suppression

The analysis of the fine structure of TEOAEs revealed that the tinnitus subjects involved in this study might, possibly, have a minor dysfunction of the cochlear active mechanisms that resulted in frequency components with lower reproducibility. Conversely, the analysis of suppression effects in the narrow-band frequency components of TEOAE indicated that the subjects involved showed no relevant damage to the efferent regulatory mechanisms that control the cochlear activity, neither through the cochlea as a whole, nor in limited cochlear regions.

from Auris Nasus Larynx

Quantitative analysis of cochlear active mechanisms in tinnitus subjects with normal hearing sensitivity: Time–frequency analysis of transient evoked otoacoustic emissions and contralateral suppression

The analysis of the fine structure of TEOAEs revealed that the tinnitus subjects involved in this study might, possibly, have a minor dysfunction of the cochlear active mechanisms that resulted in frequency components with lower reproducibility. Conversely, the analysis of suppression effects in the narrow-band frequency components of TEOAE indicated that the subjects involved showed no relevant damage to the efferent regulatory mechanisms that control the cochlear activity, neither through the cochlea as a whole, nor in limited cochlear regions.

from Auris Nasus Larynx